Absci Corporation
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Range $9 – $16
Price Chart
About the company
Absci Corporation operates as a biopharmaceutical company primarily focused on discovering novel drug targets and developing new therapeutic compounds. Leveraging its distinctive integrated drug creation platform, the firm generates potential biologic medicines and essential cell lines for manufacturing, which it provides to its collaborators, predominantly within the United States. This advanced platform is instrumental in facilitating the development of biologics by meticulously integrating the traditionally separate stages of drug discovery and cell line engineering into one streamlined process.
- CEO
- Sean McClain
- IPO
- 2021
- Employees
- 140
- HQ
- Vancouver, WA, US
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Similar companies
Peers in the same neighborhood.
- Market Cap
- $1.57B
- P/E
- -11.60
- Fwd P/E
- 3712.00
- PEG
- -0.69
- P/S
- 1007.07
- P/B
- 5.94
- EV/EBITDA
- -13.35
- Div Yield
- 0.00%
- Gross Margin
- -255.93%
- Op Margin
- -8411.27%
- Net Margin
- -7756.37%
- ROE
- -59.21%
- ROIC
- -52.24%
Latest fiscal year · YoY change
- Revenue
- $2.80M-38.2%
- Gross Profit
- $-8,942,000+84.6%
- Op Income
- $-124,718,000
- Net Income
- $-115,183,000-11.7%
- EPS
- $-0.84+10.6%
- OCF Growth
- -28.3%
- FCF Growth
- -29.2%
- 52W High
- $12.05
- 52W Low
- $2.24
- 50D MA
- $8.90
- 200D MA
- $4.94
- Beta
- 2.42
- RSI (14)
- 54
- Avg Volume
- 5.07M
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
Absci said ABS-201 is progressing on plan, with positive early safety/PK data, a Lilly partnership, and a $100 million financing that extends runway into the second half of 2028.· August 11, 2026
- Positive interim Phase I data for ABS-201 showed favorable safety/tolerability and an estimated half-life of at least 65 days.
- Management said the PK profile supports dosing 2 to 3 times over 6 months, with modeling suggesting greater than 90% receptor occupancy.
- Eli Lilly made a $40 million strategic investment and joined the endometriosis advisory board, but the company said it retains rights and plans to develop ABS-201 itself.
- Absci completed a $100 million financing in June; net proceeds from the underwritten offering were approximately $93.6 million.
- Cash, cash equivalents, and marketable securities were $201.1 million at 06/30/2026, and management said that funds the operating plan into the second half of 2028.
Absci reported research and development expense of $22.6 million for the three months ended 06/30/2026, up from $20.5 million in the prior-year period. Selling, general and administrative expense was $9.2 million versus $8.5 million a year ago. Cash, cash equivalents, and marketable securities were $201.1 million at 06/30/2026, up from $125.7 million at 03/31/2026. The company said net proceeds from the June underwritten offering were approximately $93.6 million. On ABS-201, management said interim Phase I data showed the drug was well tolerated, with half-life estimated at least 65 days and modeling suggesting more than 90% receptor occupancy with 2 to 3 doses over 6 months. Forward-looking guidance: Absci expects an interim 13-week proof-of-concept readout later this year, full 26-week proof-of-concept data in early 2027, and plans to initiate a Phase II endometriosis study in the fourth quarter of 2026; it also said cash is sufficient to fund the operating plan into the second half of 2028.
Sean McClain emphasized that ABS-201 validates the company’s AI-driven design approach and said the prolactin receptor is an underappreciated mechanism with potential across multiple diseases. He framed the Lilly investment and the $100 million financing as validation and said the company is excited about the platform’s ability to surface new indications through Atlas. His tone was confident and enthusiastic, with repeated emphasis on execution, optionality, and upcoming data readouts.
Zachariah Jonasson said the strategy remains focused on high-ROI programs, especially ABS-201 in pattern hair loss and endometriosis, while also advancing preclinical I&I programs. He cited the $22.6 million R&D expense and $9.2 million SG&A expense, both above the prior-year period, and highlighted the $201.1 million cash balance. He said the June offering added approximately $93.6 million in net proceeds and that the balance sheet supports key catalysts, pipeline progress, and an expanded planned endometriosis trial, with cash sufficient into the second half of 2028.
Analysts focused on the renaming of the lead indication from androgenetic alopecia to pattern hair loss, and management said the change was meant to better reflect the biology and the consumer-facing market, not a change in the underlying indication or market size. Questions also centered on what investors should expect from the 13-week interim readout, with management saying it expects to disclose target area hair count, hair width, darkness, and updated safety/tolerability, but not durability yet. On partnerships and platform output, management said the Lilly deal counts as the major pharma partnership they were targeting, and that future assets will be advanced with commercialization and ROI in mind, with some programs potentially partnered and others kept in-house.
The bull case is that ABS-201 has an unusually long half-life, management believes 2 to 3 doses over 6 months can achieve sustained receptor occupancy above 90%, and the company says this could support durable regenerative hair growth. Lilly’s $40 million investment and participation on the endometriosis advisory board lend external validation, while Atlas appears to be expanding the target pipeline. The balance sheet is also stronger after the financing, giving Absci room to reach multiple near-term catalysts without immediate funding pressure.
The biggest risk remains clinical: management repeatedly said the 13-week readout is only interim and that durability will not be answered in either the 13- or 26-week data. The company is still early, with key readouts not expected until later this year and early 2027, and the endometriosis trial is only planned to start in Q4 2026. Investors also have to accept that the company is still spending heavily on R&D and SG&A while the commercial case for ABS-201 remains unproven.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 86.7%
- Shares Outstanding
- 169.40M
- Float Shares
- 146.89M
of shares held by institutions
171 13F filers
Buy/sell ratio 7.50. Sells can include pre-scheduled 10b5-1 plan sales, not just discretionary selling.
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Fmr LLC | 25.41M | ▲ 2.86M |
| Ark Investment Management LLC | 12.93M | ▼ 800.90K |
| Blackrock, Inc. | 12.18M | ▲ 920.11K |
| State Street Corp | 8.10M | ▲ 772.45K |
| Vanguard Group Inc | 7.91M | ▲ 628.29K |
| Ameriprise Financial Inc | 6.99M | ▲ 3.81M |
| Redmile Group, LLC | 6.74M | ▼ 1.51M |
| Vanguard Capital Management LLC | 6.12M | ▲ 236.04K |
| Advanced Micro Devices Inc | 5.71M | 0 |
| Adage Capital Partners Gp, L.L.C. | 5.70M | ▲ 5.70M |
| Two Sigma Investments, LP | 5.49M | ▲ 2.59M |
| D. E. Shaw & Co., Inc. | 5.24M | ▲ 4.59M |
Held by 187 ETFs
Biggest fund positions in ABSI by dollar value.
Recent insider transactions
Who's buying, who's selling, and how much.
| Date | Insider | Type | Shares |
|---|---|---|---|
| Mar 3, 26 | Somaratne Ransi Mudalinayake | other | 650,000 |
| Aug 3, 26 | Somaratne Ransi Mudalinayake | other | 383,000 |
| Mar 3, 26 | Somaratne Ransi Mudalinayake | other | 0 |
| Jun 30, 26 | Szela Mary T | buy | 12,900 |
| Jun 24, 26 | McClain Sean | other | 59,896 |
| Jun 4, 26 | Szela Mary T | other | 33,200 |
| Jun 4, 26 | Szela Mary T | other | 8,400 |
| Jun 4, 26 | MCGINNIS KAREN K | other | 10,100 |
| Jun 4, 26 | MCGINNIS KAREN K | other | 39,800 |
| Jun 4, 26 | Szela Mary T | other | 39,800 |
A “Sell” may be a pre-scheduled 10b5-1 plan sale rather than a discretionary decision — read insider selling with that in mind.
Our ABSI coverage
Recent articles, reports, and earnings notes.
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