Aethlon Medical, Inc.
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Range $1.5 – $1.5
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About the company
Aethlon Medical, Inc. operates as a medical technology enterprise, dedicated to innovating solutions for the diagnosis and treatment of life-threatening and organ-jeopardizing diseases within the United States. Central to its pipeline is the Aethlon Hemopurifier, a clinical-stage immunotherapeutic device.
- CEO
- James Frakes
- IPO
- 1999
- Employees
- 9
- HQ
- San Diego, CA, US
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Similar companies
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- Market Cap
- $3.21M
- P/E
- -0.52
- Fwd P/E
- 87.00
- PEG
- -0.00
- P/S
- 0.00
- P/B
- 0.45
- EV/EBITDA
- 0.21
- Div Yield
- 0.00%
- Gross Margin
- 0.00%
- Op Margin
- 0.00%
- Net Margin
- 0.00%
- ROE
- -123.09%
- ROIC
- -127.19%
Latest fiscal year · YoY change
- Revenue
- $0+0.0%
- Gross Profit
- $0+0.0%
- Op Income
- $-7,293,631
- Net Income
- $-7,151,469+46.6%
- EPS
- $-10.61+87.6%
- OCF Growth
- +8.5%
- FCF Growth
- +8.4%
- 52W High
- $38.50
- 52W Low
- $1.41
- 50D MA
- $3.61
- 200D MA
- $8.48
- Beta
- 1.40
- RSI (14)
- 64
- Avg Volume
- 2.56M
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
Aethlon said it is in the final cohort of its Australian oncology trial, with encouraging but still preliminary biomarker signals, while keeping spending tight and bolstering cash.· August 13, 2026
- Final cohort of the Australian oncology trial has started; management expects treatment and follow-up to finish by end-2026 or early-2027.
- Preliminary Cohort 2 raw data showed decreases in extracellular vesicles and cancer-linked microRNAs, plus increases in lymphocyte subsets, but management stressed the findings are not yet statistically analyzed.
- Management is exploring Hemopurifier applications beyond oncology, including Long COVID, lupus, and heart disease in chronic kidney disease, but says broader clinical work will likely require capital, a partner, or grants.
- Cash was about $4.9 million at June 30, 2026, and the company raised about $4 million gross after quarter-end in a public offering.
- Operating expenses fell 11.9% to about $1.6 million, reflecting lower professional fees and lower G&A/preclinical research costs.
Aethlon did not discuss revenue or EPS on the call. Consolidated operating expenses for the first fiscal quarter ended June 30, 2026 were approximately $1.6 million, down 11.9% from $1.8 million in the prior-year quarter. Cash and cash equivalents were approximately $4.9 million at June 30, 2026, and the company raised approximately $4 million in gross proceeds after quarter-end through a public offering of common stock. Management said current cash resources are sufficient to fund operations for at least the next 12 months. Forward-looking commentary centered on completing the Australian oncology trial by the end of calendar 2026 or early 2027, with the next earnings call expected in November 2026 alongside the fiscal second-quarter 10-Q.
Jim Frakes framed the quarter as continued execution across clinical development, platform expansion, intellectual property growth, and disciplined resource management. He emphasized that the company is advancing the Hemopurifier while controlling costs, and pointed to the move into the final oncology cohort and expanding preclinical work beyond oncology as key progress markers. His tone was cautious but constructive, repeatedly tying future progress to disciplined capital management and further data.
Frakes highlighted a relatively lean cost base, with operating expenses down 11.9% to about $1.6 million versus $1.8 million a year ago, driven by lower professional fees and reduced general and administrative and preclinical research costs. He said the company had about $4.9 million in cash and cash equivalents at quarter-end and added roughly $4 million in gross proceeds after quarter-end via a public offering. He stated that, based on current plans, the company believes it has enough cash to fund operations for at least 12 months.
Analysts focused on whether Cohort 2’s apparent biomarker effects are lasting longer than Cohort 1’s and whether that could support a future efficacy study design. LaRosa said Cohort 2 looked more consistent across participants and showed positive directional changes lasting as far out as 8 weeks in some raw-data observations, but stressed this is preliminary and not yet statistically analyzed; he said Cohort 3 will be निर्णative. On broader programs, Frakes said additional disease research can continue in-house at low cost, but clinical trials would likely need outside capital, a partner, or grants; he also mentioned possible FDA discussions about expanding breakthrough designation, but called it only a possibility.
The company has started the final oncology cohort and says it is seeing encouraging preliminary biomarker trends, including more consistent and longer-lasting directional changes in Cohort 2. Management also believes the balance sheet is sufficient for at least 12 months and that low-cost preclinical work could create optionality across multiple indications.
The most important clinical signals remain preliminary, based on raw data from a small number of participants and without formal statistical analysis yet. Management also acknowledged that moving beyond exploratory work into clinical trials for other diseases will likely require more capital, a partner, or grants, and the company still depends on completing the final cohort before any stronger conclusions can be drawn.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 89.3%
- Shares Outstanding
- 526.71K
- Float Shares
- 470.27K
of shares held by institutions
12 13F filers
Buy/sell ratio 1.33. Sells can include pre-scheduled 10b5-1 plan sales, not just discretionary selling.
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Hrt Financial LP | 72.74K | ▲ 72.74K |
| Citadel Advisors LLC | 42.98K | ▲ 42.98K |
| Jane Street Group, LLC | 38.88K | ▲ 38.88K |
| Shay Capital LLC | 31.07K | ▲ 16.95K |
| Virtu Financial LLC | 27.82K | ▲ 27.82K |
| Ikarian Capital, LLC | 14.36K | 0 |
| Geode Capital Management, LLC | 10.19K | ▼ 14.18K |
| Scientech Research LLC | 10.05K | ▲ 10.05K |
| Ubs Group AG | 8.88K | ▲ 7.98K |
| Tower Research Capital LLC (Trc) | 6.33K | ▲ 4.72K |
| Morgan Stanley | 2.47K | ▲ 425 |
| Jones Financial Companies Lllp | 17 | ▲ 17 |
Recent insider transactions
Who's buying, who's selling, and how much.
| Date | Insider | Type | Shares |
|---|---|---|---|
| Jun 30, 26 | Shah Chetan | other | 2,182 |
| Jun 30, 26 | Gikakis Nicolas | other | 2,182 |
| Jun 30, 26 | BROENNIMAN EDWARD G | other | 1,091 |
| Apr 17, 26 | Rossetti Angela | other | 21,815 |
| Apr 17, 26 | Shah Chetan | other | 21,815 |
| Apr 17, 26 | BROENNIMAN EDWARD G | other | 21,815 |
| Apr 17, 26 | Gikakis Nicolas | other | 21,815 |
| Mar 31, 26 | Shah Chetan | other | 178 |
| Mar 31, 26 | Gikakis Nicolas | other | 178 |
| Mar 31, 26 | BROENNIMAN EDWARD G | other | 89 |
A “Sell” may be a pre-scheduled 10b5-1 plan sale rather than a discretionary decision — read insider selling with that in mind.
Our AEMD coverage
Recent articles, reports, and earnings notes.
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Generate AEMD report →Aethlon Medical, Inc. (AEMD) Shareholder/Analyst Call Prepared Remarks Transcript
seekingalpha.com · Oct 1
SHAREHOLDER ALERT: The M&A Class Action Firm Announces An Investigation of Aethlon Medical, Inc. (NASDAQ: AEMD)
gurufocus.com · Sep 18
SHAREHOLDER ALERT: The M&A Class Action Firm Announces An Investigation of Aethlon Medical, Inc. (NASDAQ: AEMD)
prnewswire.com · Sep 18
Aethlon Stock Pulls Back: What's Going On?
benzinga.com · Sep 18
BRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Ruger & Company, Inc. (NYSE – RGR), Atkore, Inc. (NYSE – ATKR), Centerspace (NYSE – CSR), Aethlon Medical, Inc. (Nasdaq – AEMD)
globenewswire.com · Sep 17
Aethlon Medical Pivots to Biotechnology with All-Stock Merger
benzinga.com · Sep 17
AEMD Stock Alert: Halper Sadeh LLC is Investigating Whether Aethlon Medical, Inc. is Obtaining a Fair Price for its Shareholders
businesswire.com · Sep 17
Aethlon Medical & North Immunology Announce Merger to Advance Novel IL-13 x IL-18 Bispecific Antibody for Atopic Dermatitis
prnewswire.com · Sep 17
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