Brainstorm Cell Therapeutics Inc.
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About the company
Brainstorm Cell Therapeutics Inc. (BCLI) is a biotechnology firm dedicated to the development and commercialization of personalized, autologous cellular therapies. These innovative treatments are specifically designed to address neurodegenerative diseases.
- CEO
- Chaim Lebovits
- IPO
- 2003
- Employees
- 20
- HQ
- New York City, NY, US
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- Market Cap
- $11.70M
- P/E
- -1.12
- Fwd P/E
- 0.80
- PEG
- -0.02
- P/S
- 0.00
- P/B
- -0.98
- EV/EBITDA
- -1.34
- Div Yield
- 0.00%
- Gross Margin
- 0.00%
- Op Margin
- 0.00%
- Net Margin
- 0.00%
- ROE
- 102.89%
- ROIC
- 94.41%
Latest fiscal year · YoY change
- Revenue
- $0+0.0%
- Gross Profit
- $0+100.0%
- Op Income
- $-9,953,000
- Net Income
- $-10,307,000-188.7%
- EPS
- $-1.11-150.7%
- OCF Growth
- +23.3%
- FCF Growth
- +23.3%
- 52W High
- $1.69
- 52W Low
- $0.46
- 50D MA
- $0.95
- 200D MA
- $0.75
- Beta
- 0.23
- RSI (14)
- 54
- Avg Volume
- 26.74K
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
Brainstorm said it is operationally ready for ENDURANCE, but funding uncertainty and a NASDAQ move to OTCQB remain the main near-term overhangs.· August 14, 2025
- FDA cleared the Phase IIIb ENDURANCE trial under a Special Protocol Assessment, which management said provides regulatory clarity.
- The company is preparing manufacturing with Minaris Advanced Therapies in New Jersey and Pluri in Israel to support trial supply.
- Management highlighted the citizens petition as a potential catalyst for a de novo review or even a path to BLA submission with a confirmatory trial.
- The stock moved from NASDAQ Capital Market to OTCQB after noncompliance with minimum shareholder equity requirements.
- Cash was approximately $1 million at June 30, 2025, underscoring the need for new funding.
For the quarter ended June 30, 2025, research and development expense was $1.1 million versus approximately $0.9 million a year earlier. General and administrative expense was approximately $1.4 million versus $2.1 million in the prior-year quarter. Net loss was approximately $2.9 million, or $0.34 per share, versus a net loss of approximately $2.5 million, or $0.60 per share, in Q2 2024. Cash, cash equivalents and restricted cash were approximately $1 million at June 30, 2025. The company did not provide formal revenue or forward financial guidance on the call; instead, it said it is actively exploring alternative funding and remains ready to initiate the Phase IIIb trial as soon as it gets a signal and financing.
Chaim Lebovits framed the quarter around one core priority: advancing NurOwn into the planned Phase IIIb ENDURANCE trial in early-stage ALS. He emphasized the FDA clearance and SPA as important derisking events, and said the citizens petition could create a potential regulatory path for accelerated approval conditioned on a confirmatory trial. His tone was cautiously optimistic, but he acknowledged that financing delays and the OTCQB move are real setbacks.
Alla Patlis reported Q2 2025 R&D expense of $1.1 million, G&A expense of $1.4 million, and a net loss of $2.9 million, or $0.34 per share. She also said cash, cash equivalents and restricted cash were approximately $1 million as of June 30, 2025. She did not discuss debt, cash burn guidance, or capital allocation plans beyond the company’s broader need to secure funding.
Analysts and investors focused on when ENDURANCE could start, what the citizens petition might change, and whether Brainstorm still plans to regain NASDAQ compliance. Management said the company is operationally ready but needs funding, and that the petition has changed the regulatory dynamic and caused investors to pause. On endpoints, management reiterated that ALSFRS-R remains the primary endpoint under the SPA, while survival, biomarkers, quality of life and real-world evidence are supportive or exploratory rather than replacements.
The bull case from the call is that Brainstorm believes it has a clearer regulatory path than before: FDA-cleared trial design, SPA agreement, and a citizens petition that could prompt a fresh look at existing data. Management also pointed to long-term survival observations from the expanded access program and said the platform may have broader CNS potential beyond ALS.
The main bear case is funding: management said it could not close the financing needed to launch the trial and maintain NASDAQ equity compliance, and cash was only about $1 million at quarter-end. The OTCQB transition highlights balance-sheet pressure, and the company also acknowledged that the citizens petition has created a wait-and-see posture among investors rather than immediate support.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 70.5%
- Shares Outstanding
- 11.03M
- Float Shares
- 7.78M
of shares held by institutions
33 13F filers
Buy/sell ratio 0.00. Sells can include pre-scheduled 10b5-1 plan sales, not just discretionary selling.
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Blackrock Inc. | 386.41K | ▼ 102.90K |
| Raymond James & Associates | 95.15K | ▼ 16.13K |
| Institutional & Family Asset Management, LLC | 6.00K | 0 |
Held by 1 ETFs
Biggest fund positions in BCLI by dollar value.
Recent insider transactions
Who's buying, who's selling, and how much.
| Date | Insider | Type | Shares |
|---|---|---|---|
| Jul 24, 26 | FRENKEL JACOB A | other | 100,000 |
| Jul 24, 26 | Pitts Peter Joe | other | 900,000 |
| May 25, 26 | Pitts Peter Joe | other | 150,000 |
| Feb 26, 26 | Lebovits Chaim | other | 1,800,000 |
| Feb 26, 26 | Yablonka Uri | other | 150,000 |
| Feb 26, 26 | Patlis Alla | other | 100,000 |
| Feb 26, 26 | FRENKEL JACOB A | other | 200,000 |
| Feb 26, 26 | ARBEL IRIT | other | 120,000 |
| Feb 26, 26 | Bairu Menghisteab | other | 150,000 |
| Feb 26, 26 | Polverino Anthony J. | other | 150,000 |
A “Sell” may be a pre-scheduled 10b5-1 plan sale rather than a discretionary decision — read insider selling with that in mind.
Our BCLI coverage
Recent articles, reports, and earnings notes.
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Generate BCLI report →BrainStorm Cell Therapeutics Announces Second Quarter 2026 Financial Results and Provides Corporate Update
prnewswire.com · Aug 14
BrainStorm Appoints Former FDA Associate Commissioner Peter J. Pitts as Executive Chairman
prnewswire.com · Jul 28
BrainStorm Cell Therapeutics Announces Publication Calling for Updated FDA Approaches to ALS, Rare Diseases and Regenerative Medicine
prnewswire.com · Jun 2
BrainStorm Cell Therapeutics Appoints Former FDA Associate Commissioner Peter J. Pitts to Board of Directors
prnewswire.com · May 28
BrainStorm Cell Therapeutics Announces Aggregate of $400,000 in Private Placements Priced at Premium to Market
prnewswire.com · May 19
BrainStorm Cell Therapeutics Announces First Quarter 2026 Financial Results and Provides Corporate Update
prnewswire.com · May 15
Comparing Brainstorm Cell Therapeutics (NASDAQ:BCLI) and Zealand Pharma A/S (OTCMKTS:ZLDPF)
defenseworld.net · Apr 18
Brainstorm Cell Therapeutics (NASDAQ:BCLI) Shares Pass Above Two Hundred Day Moving Average – Here’s What Happened
defenseworld.net · Apr 8
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