Cybin Inc.
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About the company
Cybin Inc. is a biopharmaceutical firm dedicated to pioneering treatments that leverage psychedelic compounds. Its research and development portfolio encompasses several key candidates: CYB003, a modified psilocybin compound targeting major depressive and alcohol use disorders; CYB004, a deuterated dimethyltryptamine designed to alleviate anxiety conditions; and CYB005, a phenethylamine derivative aimed at combating neuroinflammation.
- CEO
- Eric So
- IPO
- 2019
- Employees
- 50
- HQ
- Toronto, ON, CA
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- Market Cap
- $413.02M
- P/E
- -2.96
- Fwd P/E
- 2.51
- PEG
- -0.13
- P/S
- 0.00
- P/B
- 2.70
- EV/EBITDA
- -0.82
- Div Yield
- 0.00%
- Gross Margin
- 0.00%
- Op Margin
- 0.00%
- Net Margin
- 0.00%
- ROE
- -74.47%
- ROIC
- -70.77%
Latest fiscal year · YoY change
- Revenue
- $0+0.0%
- Gross Profit
- $-330,049+22.2%
- Op Income
- $-143,147,000
- Net Income
- $-113,137,000-44.9%
- EPS
- $-0.61+84.4%
- OCF Growth
- -47.0%
- FCF Growth
- -48.3%
- 52W High
- $10.72
- 52W Low
- $4.81
- 50D MA
- $6.69
- 200D MA
- $6.99
- Beta
- 0.79
- RSI (14)
- 39
- Avg Volume
- 874.38K
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
Cybin said it strengthened its balance sheet and kept both late-stage programs on track, with CYB004 on pace for 1Q 2026 data and CYB003 progressing toward a Q4 2026 top-line readout.· November 13, 2025
- CYB004 completed enrollment and remains on track for first-quarter 2026 top-line data; management said it wants directional separation between doses and would be thrilled by statistical significance.
- CYB003 Phase III work continued, with APPROACH dosing underway and EMBRACE cleared in the U.S., U.K., EU and Australia across about 60 sites and about 330 participants.
- The company closed a $175 million financing and used part of the proceeds to repay High Trail debt, which Greg Cavers said totaled $20 million with a 10% repayment fee.
- Management emphasized a clinic-friendly, staff-light commercial model built around short sessions, existing infrastructure, and durability/retreatment approaches to reduce visit burden.
- Cash at quarter-end was $83.8 million; management said that, together with the new financing, it expects funding into 2027 and through key 2026 data readouts.
For the quarter ended September 30, 2025, cash-based operating expenses were $28.5 million versus $18.2 million a year ago. Operating loss was $28.9 million; net loss was $33.7 million, or $1.39 per basic and diluted share, versus a net loss of $41.9 million in the prior-year period. Cash flows used in operating activities were $34.5 million versus $19.1 million last year, and the company ended the quarter with $83.8 million of cash, cash equivalents and investments. Subsequent to quarter-end, Cybin closed a $175 million financing, repaid $20 million of High Trail debt with a 10% repayment fee, and said current resources should fund key data readouts in 2026 and operations into 2027.
Eric So framed the quarter as a transition-and-execution period, noting his move into the interim CEO role after Doug Drysdale stepped down. His message centered on discipline: tighter operating cadence, clearer disclosure, selective hiring, and capital deployment tied to specific milestones. Strategically, he kept returning to the idea that Cybin’s programs must fit into real clinic workflows, with predictable sessions, simple staffing, and durability that lowers visit burden.
Greg Cavers reported $28.5 million of cash-based operating expenses for the quarter, $28.9 million of operating loss, and $33.7 million of net loss, or $1.39 per share. He said the company ended the quarter with $83.8 million in cash, cash equivalents and investments, then added that the post-quarter $175 million financing gives Cybin flexibility to execute its plan. He also said the company expects its cash resources to fund key data readouts in 2026 and operations into 2027.
Analysts focused on what would count as success for CYB004 and how that program could advance into Phase III; management said it is a proof-of-concept study, not formally powered, and that directional improvement and dose response are the main goals, though statistical significance would be welcome. On CYB003, management said enrollment should finish by mid-2026 and top-line data should arrive by the end of 2026, while also saying 12 weeks of durability would meet the agency’s minimum expectation and that the company is aiming higher based on prior 12-month Phase II durability. Management also said payer engagement has begun, site selection is emphasizing data quality and experience, and the CEO search is active but still in progress.
The bull case from the call is that both lead programs remain on schedule, with CYB004 enrolled and CYB003 expanding globally toward meaningful data milestones. Management also pointed to an improved balance sheet after the $175 million financing, plus a clinic-ready product concept that could fit into existing interventional psychiatry workflows.
The bear case is that Cybin is still pre-commercial and pre-pivotal readouts, so the story remains highly dependent on upcoming clinical data. CYB004 is not formally powered, making interpretation of the 1Q 2026 readout more subjective, and management repeatedly acknowledged that payer work is still early. The CEO transition also remains unresolved, with the search for a permanent CEO still underway.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 77.3%
- Shares Outstanding
- 49.88M
- Float Shares
- 38.55M
of shares held by institutions
78 13F filers
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Emfo, LLC | 24.48K | 0 |
| Peak6 Investments LLC | 11.37K | ▼ 420.51K |
| Planning Capital Management Corp | 26 | ▼ 974 |
Our CYBN coverage
Recent articles, reports, and earnings notes.
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