Cryoport, Inc.
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Range $13.5 – $25
Price Chart
About the company
Cryoport, Inc. operates as a specialized service provider within the life sciences sector, delivering global temperature-controlled supply chain solutions across the Americas, Europe, the Middle East, Africa, and the Asia Pacific region. Central to their offerings is Cryoportal, a proprietary cloud-based platform designed to streamline the entire logistics process.
- CEO
- Jerrell W. Shelton
- IPO
- 2005
- Employees
- 688
- HQ
- Brentwood, TN, US
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Similar companies
Peers in the same neighborhood.
- Market Cap
- $845.25M
- P/E
- -20.45
- PEG
- 0.13
- P/S
- 4.53
- P/B
- 1.72
- EV/EBITDA
- -258.23
- Div Yield
- 0.00%
- Gross Margin
- 47.08%
- Op Margin
- -21.25%
- Net Margin
- -19.45%
- ROE
- -7.25%
- ROIC
- -5.46%
Latest fiscal year · YoY change
- Revenue
- $176.18M-24.5%
- Gross Profit
- $83.05M-16.4%
- Op Income
- $-36,806,000
- Net Income
- $78.30M+178.6%
- EPS
- $1.40+163.3%
- OCF Growth
- +47.4%
- FCF Growth
- +16.4%
- 52W High
- $16.89
- 52W Low
- $7.61
- 50D MA
- $15.40
- 200D MA
- $11.39
- Beta
- 1.89
- RSI (14)
- 65
- Avg Volume
- 774.20K
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
Cryoport posted $49 million of second-quarter revenue, turned positive adjusted EBITDA, and reiterated full-year 2026 revenue guidance of $192 million to $196 million despite saying it is being conservative amid macro and geopolitical uncertainty.· August 6, 2026
- Total revenue was $49 million, with Life Science Services up 15% year over year and Life Science Products showing solid demand, especially from MVE biological systems.
- Adjusted EBITDA from continuing operations improved by $1.3 million year over year to positive $400,000, an important profitability milestone.
- Cell and gene therapy activity remained a growth engine: commercial therapy revenue rose 9% to $9.4 million and clinical trial support revenue rose 12% to $13.4 million.
- Management kept full-year 2026 revenue guidance unchanged at $192 million to $196 million, citing prudence given geopolitical and macro uncertainty.
- The company highlighted strategic progress in IntegriCell, China manufacturing, new facilities in Paris and Santa Ana, and AI-driven efficiency efforts.
Cryoport reported second-quarter total revenue of $49 million. Life Science Services revenue grew 15% year over year, driven by 25% growth in biostorage and bioservices. Revenue supporting commercial cell and gene therapies rose 9% to $9.4 million, while revenue supporting cell and gene therapy clinical trials increased 12% to $13.4 million. Adjusted EBITDA from continuing operations improved by $1.3 million year over year to positive $400,000. Management reaffirmed full-year 2026 revenue guidance of $192 million to $196 million. On the cash side, the company said it generated approximately $5 million of positive net cash from operating activities in the first half of 2026, up $17 million versus the first half of 2025.
Jerrell Shelton said the quarter showed continued revenue momentum, stronger profitability, and progress across the company’s integrated temperature-controlled supply chain platform. He emphasized Cryoport’s leadership in cell and gene therapy support, the importance of new commercial approvals and clinical pipeline growth, and the long-term opportunity in standardizing services like IntegriCell and expanding global infrastructure. His tone was confident but measured, especially on guidance, where he said holding the range was prudent because of global uncertainty.
Robert Stefanovich focused on the financial trajectory, saying the key assumptions behind 2026 outlook were largely unchanged and demand remains robust across both Life Science Services and Life Science Products. He highlighted that positive adjusted EBITDA in Q2 showed the strategy is working, and said higher utilization of the global supply chain center network should drive additional operating leverage and more EBITDA expansion. He also pointed to approximately $5 million of positive operating cash flow in the first half of 2026, a $17 million improvement year over year, as evidence of the path to sustainable profitability.
On guidance, analysts asked why full-year revenue guidance was unchanged despite first-half revenue of about $97 million and a Q2 beat. Management said it was a prudent stance because of geopolitical and macro uncertainty, not a change in underlying business fundamentals. On products growth, management said the outlook is still in the upper single digits and that MVE is on solid ground, with the business remaining a strong cash generator. Questions on China, IntegriCell, and the Fusion freezer drew responses that these are important strategic opportunities, but IntegriCell will ramp slowly due to regulatory and workflow adoption hurdles, while China production is intended to improve competitiveness and avoid tariffs.
The call showed broad-based operational momentum: services, products, commercial therapy support, and clinical trial activity all grew. Management also pointed to positive adjusted EBITDA, improving operating cash flow, and expectations for further operating leverage as utilization rises. The company believes it has multiple longer-term catalysts, including new facilities, China manufacturing, IntegriCell adoption, and new product launches like Fusion.
Management repeatedly flagged uncertainty as the reason for holding guidance flat, which suggests limited visibility in the second half. IntegriCell is not expected to be a meaningful 2026 revenue contributor and will take time to overcome regulatory and operational adoption hurdles. China revenue is still only about 2% to 3% of total revenue, and management said the service-side strategy there is still being defined.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 86.9%
- Shares Outstanding
- 50.40M
- Float Shares
- 43.82M
of shares held by institutions
172 13F filers
Buy/sell ratio 0.00. Sells can include pre-scheduled 10b5-1 plan sales, not just discretionary selling.
Congressional trading
Senate and House stock disclosures for CYRX, newest first.
| Member | Type | Traded | |
|---|---|---|---|
| Josh GottheimerHouse · NJ05 | Sell | Sep 15, 23 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Sell | Feb 28, 22 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Sell | Jan 14, 22 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Sell | Jan 31, 22 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Sell | Jan 13, 22 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Sell | Sep 21, 21 | Filing → |
| Gilbert CisnerosHouse · CA31 | Sell | Nov 24, 20 | Filing → |
| Josh GottheimerHouse · NJ05 | Sell | Nov 13, 20 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Buy | Nov 2, 20 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Buy | Nov 17, 20 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Sell | Jul 14, 20 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Sell | May 7, 20 | Filing → |
| Gilbert CisnerosHouse · CA31 | Buy | Feb 6, 20 | Filing → |
| Donald Sternoff BeyerHouse · VA08 | Buy | Jan 13, 20 | Filing → |
Source: public STOCK Act disclosures. Filed weeks after the trade — a lagging signal, not a real-time one.
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Blackrock, Inc. | 4.22M | ▲ 237.54K |
| Cadian Capital Management, LP | 2.92M | ▼ 1.86M |
| Vanguard Group Inc | 2.91M | ▲ 47.92K |
| Morgan Stanley | 2.28M | ▼ 2.30M |
| Vanguard Capital Management LLC | 2.15M | ▲ 33.09K |
| Millennium Management LLC | 1.72M | ▼ 1.25M |
| Thematics Asset Management | 1.64M | ▼ 276.26K |
| Fred Alger Management, LLC | 1.55M | ▼ 154.09K |
| Geode Capital Management, LLC | 1.31M | ▲ 64.23K |
| Mak Capital One LLC | 1.28M | ▼ 145.91K |
| First Eagle Investment Management, LLC | 1.27M | ▲ 526.58K |
| Assenagon Asset Management S.A. | 1.15M | ▼ 343.37K |
Held by 132 ETFs
Biggest fund positions in CYRX by dollar value.
Recent insider transactions
Who's buying, who's selling, and how much.
| Date | Insider | Type | Shares |
|---|---|---|---|
| Aug 11, 26 | SHELTON JERRELL | sell | 28,800 |
| Jun 11, 26 | ZECCHINI EDWARD J | other | 33,600 |
| Jun 10, 26 | ZECCHINI EDWARD J | other | 1,400 |
| Jun 11, 26 | ZECCHINI EDWARD J | sell | 33,600 |
| Jun 10, 26 | ZECCHINI EDWARD J | sell | 1,400 |
| Jun 10, 26 | ZECCHINI EDWARD J | other | 1,400 |
| Jun 11, 26 | ZECCHINI EDWARD J | other | 33,600 |
| Jun 5, 26 | BADDOUR LINDA | other | 10,350 |
| Jun 5, 26 | BADDOUR LINDA | other | 16,077 |
| Jun 4, 26 | STEFANOVICH ROBERT | sell | 169,427 |
A “Sell” may be a pre-scheduled 10b5-1 plan sale rather than a discretionary decision — read insider selling with that in mind.
Our CYRX coverage
Recent articles, reports, and earnings notes.
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Generate CYRX report →CryoPort (CYRX) Upgraded to Buy: Here's Why
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Cryoport, Inc. (CYRX) Q2 2026 Earnings Call Transcript
seekingalpha.com · Aug 7
CryoPort Q2 Earnings Call Highlights
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CryoPort, Inc. (CYRX) Reports Q2 Loss, Beats Revenue Estimates
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Cryoport Reports Second Quarter 2026 Financial Results
prnewswire.com · Aug 6
Cryoport to Report Second Quarter 2026 Financial Results on August 6, 2026
prnewswire.com · Jul 23
Cryoport's IntegriCell® Cryopreservation Services Selected by Verismo Therapeutics to Support Clinical KIR-CAR T Cell Therapy Programs
prnewswire.com · Jun 25
Cryoport, Inc. (CYRX) Q1 2026 Earnings Call Transcript
seekingalpha.com · May 5
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