Lantern Pharma Inc.
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About the company
Lantern Pharma Inc. is a clinical-stage biotechnology firm dedicated to revolutionizing drug development through the strategic application of artificial intelligence, machine learning, and comprehensive genomic data analysis. Their primary drug candidate, LP-100, is currently undergoing Phase II clinical trials, targeting metastatic, castration-resistant prostate cancer.
- CEO
- Panna Sharma
- IPO
- 2020
- Employees
- 16
- HQ
- Dallas, TX, US
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- Market Cap
- $29.22M
- P/E
- -1.41
- PEG
- -0.22
- P/S
- 0.00
- P/B
- -8.84
- EV/EBITDA
- -1.21
- Div Yield
- 0.00%
- Gross Margin
- 0.00%
- Op Margin
- 0.00%
- Net Margin
- 0.00%
- ROE
- -456.35%
- ROIC
- -358.04%
Latest fiscal year · YoY change
- Revenue
- $0+0.0%
- Gross Profit
- $0+0.0%
- Op Income
- $-17,978,494
- Net Income
- $-17,119,438+17.6%
- EPS
- $-1.57+99.9%
- OCF Growth
- +12.0%
- FCF Growth
- +12.0%
- 52W High
- $4.70
- 52W Low
- $1.11
- 50D MA
- $3.24
- 200D MA
- $3.01
- Beta
- 2.33
- RSI (14)
- 29
- Avg Volume
- 162.39K
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
Lantern Pharma said Q2 showed continued clinical progress in LP-300 and LP-184, while a new Open Medicine AI spinout became the quarter’s biggest strategic development.· August 14, 2026
- LP-300 data in never-smoker NSCLC continued to improve, with median PFS of 8.9 months in the 6-cycle L858R group and 8.4 months across the full L858R cohort.
- Management said LP-300 protocol amendments were approved, enrollment will resume under an 8-cycle single-arm design, and another 15 to 16 patients are targeted over 4 to 6 months.
- LP-184 advanced with EMA clearance for a 39-patient bladder cancer study, FDA clearance for a TNBC trial, and a notice of allowance for a patient-selection patent covering 4 tumor types.
- Lantern formally separated Open Medicine AI as a new company with commercial licensing in place, and said it may eventually be separately listed.
- Operating loss improved year over year, even as the company absorbed a large noncash warrant-related expense tied to the May financing.
For the second quarter ended 06/30/2026, Lantern reported cash, cash equivalents, and marketable securities of approximately $7.4 million, including about $6.7 million in cash and cash equivalents and about $700 thousand in marketable securities, versus approximately $10.1 million at 12/31/2025. R&D expense was approximately $1.8 million, down from approximately $3.1 million a year ago, a decrease of about $1.3 million or 42%; G&A was approximately $1.7 million versus approximately $1.6 million, up about $130 thousand or 8%; and loss from operations was approximately $3.5 million versus approximately $4.7 million, an improvement of about 25%. After approximately $3.6 million of warrant-related expense, net loss was approximately $7.1 million, or $0.57 per share, compared with approximately $4.3 million, or $0.40 per share, in the prior-year quarter. For the six months ended 06/30/2026, net loss was approximately $10.4 million, or $0.88 per share, versus approximately $8.9 million, or $0.82 per share. Management said it received approximately $4.4 million in gross proceeds from the May 2026 registered direct offering and intends to pursue additional capital raises, collaborations, and other opportunities to extend runway.
Panna Sharma framed the quarter as an inflection point, arguing Lantern is now proving its AI-driven model in real trials while building a separate AI business. He emphasized that the company advanced multiple programs from AI-derived insights to clinical and regulatory milestones in under 3 years, and said the new Open Medicine AI structure is intended to give the platform its own capital structure and valuation path. His tone was highly confident and expansive, but he repeatedly anchored it in specific clinical and structural milestones rather than only future potential.
David Margrave focused on liquidity, spend discipline, and the accounting impact of the May financing. He highlighted approximately $7.4 million in cash, cash equivalents, and marketable securities at quarter-end, compared with approximately $10.1 million at year-end 2025, and noted approximately $4.4 million in gross proceeds from the registered direct offering. He said R&D fell 42% to approximately $1.8 million, operating loss improved 25% to approximately $3.5 million, and the quarter included approximately $3.6 million of warrant-related expense that drove net loss to approximately $7.1 million, or $0.57 per share. He also said there was no ATM activity and that additional capital is a top priority.
Analysts pressed for more detail on LP-300 data maturity, whether the amended protocol had started enrolling, and when another update might come. Management said IRB approvals are complete, enrollment should resume under the amended 8-cycle protocol in the US and Taiwan, and the next 15 to 16 patients should provide meaningful data over the next 4 to 6 months; a further update may come near year-end. On Open Medicine AI, questions focused on how the system differs from existing AI tools, adoption, and competitive defensibility; Sharma said the platform uses a multi-agent, transparent workflow, that adoption has been sticky once users try it, and that large pharma interest is increasing. He also said Lantern is considering ways to let shareholders benefit from the spinout, potentially including distribution of Open Medicine shares.
The bullish case is that Lantern is showing clinical signal across multiple programs at the same time it is reducing operating loss year over year. Management pointed to improving LP-300 durability, new trial designs and clear regulatory paths for LP-184, and a commercially oriented AI spinout that could add a second growth engine and future shareholder value.
The main risks are that the clinical datasets remain small and exploratory, especially for LP-300, which management acknowledged is not yet powered for statistical significance. The company also ended the quarter with only about $7.4 million in cash and said additional capital raises are needed, while the new Open Medicine AI strategy adds execution and financing complexity alongside ongoing biotech development risk.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 75.2%
- Shares Outstanding
- 12.76M
- Float Shares
- 9.59M
of shares held by institutions
35 13F filers
Buy/sell ratio 1.00. Sells can include pre-scheduled 10b5-1 plan sales, not just discretionary selling.
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Vanguard Group Inc | 384.04K | 0 |
| Cibc Private Wealth Group, LLC | 15.43K | ▲ 15.43K |
Held by 24 ETFs
Biggest fund positions in LTRN by dollar value.
Recent insider transactions
Who's buying, who's selling, and how much.
| Date | Insider | Type | Shares |
|---|---|---|---|
| May 12, 26 | Schalop Lee Troy | buy | 48,544 |
| May 12, 26 | Schalop Lee Troy | buy | 48,544 |
| May 12, 26 | KEYSER D JEFFREY | buy | 48,544 |
| May 12, 26 | KEYSER D JEFFREY | buy | 48,544 |
| Jan 9, 26 | KEYSER D JEFFREY | other | 28,844 |
| Jan 9, 26 | KEYSER D JEFFREY | other | 25,000 |
| Jan 9, 26 | Maccecchini Maria-Luisa | other | 25,000 |
| Jan 9, 26 | Maccecchini Maria-Luisa | other | 21,152 |
| Jan 9, 26 | Chandru Vijay | other | 25,000 |
| Jan 9, 26 | Chandru Vijay | other | 17,307 |
A “Sell” may be a pre-scheduled 10b5-1 plan sale rather than a discretionary decision — read insider selling with that in mind.
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Recent articles, reports, and earnings notes.
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Generate LTRN report →Lantern Pharma Inc. (LTRN) Q2 2026 Earnings Call Transcript
seekingalpha.com · Aug 14
Lantern Pharma Reports Second Quarter 2026 Financial Results and Provides Business Update
businesswire.com · Aug 14
Lantern Pharma to Report Second Quarter 2026 Operating & Financial Results on August 14th, 2026 at 9:00 a.m. ET
gurufocus.com · Aug 7
Lantern Pharma to Report Second Quarter 2026 Operating & Financial Results on August 14th, 2026 at 9:00 a.m. ET
businesswire.com · Aug 7
Lantern Pharma (Nasdaq: LTRN) Establishes Open-Medicine AI as a Separate Company to Commercialize and Expand Its Multi-Agent AI Co-Scientist Platform for the Transformation of Medicine
gurufocus.com · Aug 3
Lantern Pharma (Nasdaq: LTRN) Establishes Open-Medicine AI as a Separate Company to Commercialize and Expand Its Multi-Agent AI Co-Scientist Platform for the Transformation of Medicine
businesswire.com · Aug 3
Lantern Pharma to Advance EMA-Cleared Phase 1b/2 Trial of LP-184 (Zirdafulven) in Biomarker-Selected Advanced Bladder Cancer
businesswire.com · Jul 28
Lantern Pharma Receives USPTO Notice of Allowance for Patent Covering Biomarker-Guided Treatment with LP-184 (Zirdafulven) in Multiple Solid Tumor Cancers
businesswire.com · Jul 23
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