Pelthos Therapeutics Inc.
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Range $45 – $64
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About the company
Pelthos Therapeutics Inc. operates as a biopharmaceutical enterprise dedicated to developing and commercializing innovative medical treatments that address significant, unmet patient needs. Its primary offerings include ZELSUVMI, a medication specifically indicated for the treatment of molluscum contagiosum in individuals aged one year and older.
- CEO
- Scott Plesha
- IPO
- 2024
- Employees
- 92
- HQ
- Durham, NC, US
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- Market Cap
- $92.66M
- P/E
- -0.64
- Fwd P/E
- 17.44
- PEG
- 0.00
- P/S
- 2.14
- P/B
- -62.87
- EV/EBITDA
- -2.24
- Div Yield
- 0.00%
- Gross Margin
- 54.72%
- Op Margin
- -133.42%
- Net Margin
- -165.24%
- ROE
- -218.94%
- ROIC
- -49.39%
Latest fiscal year · YoY change
- Revenue
- $16.80M+0.0%
- Gross Profit
- $7.43M+0.0%
- Op Income
- $-32,430,000
- Net Income
- $-43,319,000-444.5%
- EPS
- $-23.04-70.2%
- OCF Growth
- -290.0%
- FCF Growth
- -291.7%
- 52W High
- $37.50
- 52W Low
- $18.19
- 50D MA
- $27.42
- 200D MA
- $25.96
- Beta
- 3.13
- RSI (14)
- 47
- Avg Volume
- 49.15K
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
Pelthos posted strong ZELSUVMI-driven Q2 growth, with revenue up to $15.4 million, but margins still reflected inventory step-up costs and launch spending ahead of future product rollouts.· August 13, 2026
- Net product revenue rose to $15.4 million in Q2 2026, up 45% from Q1, driven by a 48% increase in prescription units to 11,925.
- ZELSUVMI demand remained the core story: more than 30,000 units dispensed since launch, over 8,000 unique HCP prescribers, and more than 25,000 patients prescribed in the first year.
- Coverage was strong at 59% for commercial plans and 100% for Medicaid, while GTNs were 29.6% and expected to move into the mid-30% range.
- Management said Q3 seasonality should be manageable, with early indicators showing claims stable to up, despite summer volatility and holiday timing.
- The company continues preparing XEPI for a Q1 2027 launch and Xeglyze for Q3 2027, with manufacturing and inventory build ongoing.
Pelthos reported Q2 2026 net product revenue of $15.4 million, up 45% from $10.7 million in Q1 2026. Symphony-reported prescription units increased 48% from 8,084 in Q1 to 11,925 in Q2, and SG&A rose to $27.7 million from $21.1 million. Cost of goods sold was $3.6 million versus $1.7 million in Q1, including a $0.9 million write-off of commercial API inventory; net loss was $23.4 million versus $25.1 million as amended, and adjusted EBITDA was negative $5.7 million versus negative $8.0 million. As of June 30, 2026, cash was $24.2 million, accounts receivable were $14.5 million, and working capital was $31.4 million. For forward guidance, the company did not provide discrete revenue or earnings guidance, but said GTNs should move into the mid-30% range, XEPI is expected to launch in Q1 2027, and Xeglyze in Q3 2027. Management also said it expects to burn through stepped-up API inventory over the next 12 to 15 months, after having already sold through the stepped-up finished goods inventory.
Scott Plesha framed the quarter as strong execution in an early launch phase, emphasizing that ZELSUVMI is gaining traction as the first at-home treatment for molluscum contagiosum. He highlighted the PBM contract as a demand catalyst, ongoing commercial expansion, and the strategic fit of XEPI and Xeglyze with the existing field force. His tone was confident and upbeat, while still noting the company is early in the launch and has not issued discrete revenue or earnings guidance.
John Gay emphasized that Q2 revenue of $15.4 million and the trailing four-quarter total of $42.3 million reflect continued launch success, while also walking through the accounting restatement tied to fair value treatment of related-party convertible notes. He cited COGS of $3.6 million, SG&A of $27.7 million, net loss of $23.4 million, adjusted EBITDA of negative $5.7 million, and cash of $24.2 million at quarter-end. He also said the restatement does not affect cash, net revenues, product sales, operating expenses, operating loss, operating cash flows, or adjusted EBITDA, and noted the company has access to an additional $10 million under the Horizon term loan facility subject to lender discretion.
Analysts focused on seasonality, gross-to-net trends, prescription volatility, pediatric adoption, business development appetite, and readiness for XEPI and Xeglyze. Management said Q3 claims look stable so far despite expected summer softness, and that back-to-school timing and repeat writers should help normalize utilization. On GTNs, Scott said the company is currently at 29.6%, expects low- to mid-30% levels later in the year, and could move higher if a new plan contract closes; on BD, he said they are open to opportunities that fit their novel, need-based product profile rather than me-too assets.
The bullish case from the call is that ZELSUVMI continues to outperform expectations, with prescriptions, prescribers, and patient uptake all rising meaningfully in only the first year after launch. Management also pointed to improving repeat writing, strong coverage, and early evidence that seasonality may be less disruptive than feared. The upcoming XEPI and Xeglyze launches could add leverage to the existing commercial infrastructure if execution continues.
The main risks discussed were seasonality and weekly prescription volatility, especially around summer schedules, holidays, and back-to-school timing. Margins are still affected by inventory step-up accounting and a $0.9 million API write-off, while SG&A remains elevated as the company invests in growth and launch preparation. Management also acknowledged that GTNs may rise into the low- to mid-30% range, which would pressure net price realization, and that the company is still dependent on a relatively new product launch for revenue.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 30.7%
- Shares Outstanding
- 3.48M
- Float Shares
- 1.07M
of shares held by institutions
15 13F filers
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Vanguard Group Inc | 75.02K | ▲ 8.18K |
Held by 23 ETFs
Biggest fund positions in PTHS by dollar value.
Recent insider transactions
Who's buying, who's selling, and how much.
| Date | Insider | Type | Shares |
|---|---|---|---|
| Jul 2, 26 | Friedberg Ezra M | sell | 534 |
| Jul 2, 26 | Friedberg Ezra M | sell | 24 |
| Jul 2, 26 | Pauls Matthew | sell | 692 |
| Jul 2, 26 | Pauls Matthew | sell | 94 |
| Jul 2, 26 | Greenleaf Peter | sell | 712 |
| Jul 2, 26 | Greenleaf Peter | sell | 85 |
| Jun 15, 26 | Friedberg Ezra M | sell | 224 |
| Jun 15, 26 | Friedberg Ezra M | sell | 59 |
| Jun 11, 26 | Davis Todd C | buy | 503 |
| Jun 11, 26 | Davis Todd C | buy | 35,445 |
A “Sell” may be a pre-scheduled 10b5-1 plan sale rather than a discretionary decision — read insider selling with that in mind.
Our PTHS coverage
Recent articles, reports, and earnings notes.
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Generate PTHS report →Pelthos Therapeutics Q2 Earnings Call Highlights
marketbeat.com · Aug 14
Pelthos Therapeutics Inc. (PTHS) Q2 2026 Earnings Call Transcript
seekingalpha.com · Aug 13
Pelthos Therapeutics Inc. (PTHS) Reports Q2 Loss, Lags Revenue Estimates
zacks.com · Aug 13
Pelthos Therapeutics Announces Second Quarter 2026 Financial Results
globenewswire.com · Aug 13
Pelthos Therapeutics to Report Second Quarter 2026 Financial Results on August 13, 2026
globenewswire.com · Aug 3
Pelthos Therapeutics Announces 2026 Annual Meeting of Stockholders
globenewswire.com · Jul 24
Pelthos Therapeutics Added to Russell 3000E™ Growth Benchmark, Russell Microcap® and Russell Microcap® Growth Benchmark Indexes
globenewswire.com · Jun 30
Pelthos Therapeutics to Participate in 2026 Jefferies Global Healthcare Conference
globenewswire.com · May 28
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