Silence Therapeutics plc
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Companywww.silence-therapeutics.com
Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development of novel ribonucleic acid (RNA) therapeutics in hematology, cardiovascular, and other rare and metabolic indications. The company's platform includes mRNAi GalNAc Oligonucleotide Discovery platform designed to accurately target specific disease-associated genes in the liver. It designs short interfering RNA molecules to harness the body's natural mechanism of RNA interference, and degrading messenger RNA molecules that encode specific targeted disease-associated proteins in a cell.
- CEO
- Iain Gladstone Ross
- IPO
- 2020
- Employees
- 116
- HQ
- London, GB
Price Chart
Valuation
- Market Cap
- $298.05M
- P/E
- -3.97
- P/S
- 355.54
- P/B
- 6.03
- EV/EBITDA
- -4.15
- Div Yield
- 0.00%
Profitability
- Gross Margin
- 66.86%
- Op Margin
- -9267.51%
- Net Margin
- -8948.43%
- ROE
- -107.19%
- ROIC
- -74.16%
Growth & Income
- Revenue
- $559.00K · -98.71%
- Net Income
- $-88,612,000 · -95.57%
- EPS
- $-1.89 · 20.25%
- Op Income
- $-89,753,000
- FCF YoY
- 8.14%
Performance & Tape
- 52W High
- $8.40
- 52W Low
- $4.19
- 50D MA
- $6.61
- 200D MA
- $5.96
- Beta
- 1.48
- Avg Volume
- 334.12K
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Recent Insider Transactions
| Date | Insider | Type | Shares |
|---|---|---|---|
| Aug 3, 25 | Griffiths Richard Ian | buy | 20,000 |
| Oct 27, 25 | Griffiths Richard Ian | buy | 2,000 |
| Oct 27, 25 | Griffiths Richard Ian | sell | 2,000 |
| Aug 3, 25 | Griffiths Richard Ian | sell | 20,000 |
| Jan 2, 26 | Ede-Golightly James | other | 90,000 |
| Jan 2, 26 | MCINERNEY TIMOTHY | other | 90,000 |
| Jan 2, 26 | Romano Steven J. | other | 300,000 |
| Jan 2, 26 | HELLUMS RHONDA LYNETTE | other | 375,000 |
| Jan 2, 26 | Lemus David | other | 90,000 |
| Dec 18, 25 | Ross Iain | other | 900,000 |
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