BridgeBio Pharma, Inc.
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Range $97 – $130
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About the company
BridgeBio Pharma, Inc. is a pharmaceutical company dedicated to identifying, advancing, and providing medical solutions for various genetic conditions. The firm boasts an extensive portfolio comprising 30 distinct development initiatives, spanning the entire spectrum from initial discovery research to advanced clinical trial phases.
- CEO
- Neil Kumar
- IPO
- 2019
- Employees
- 999
- HQ
- Palo Alto, CA, US
AI snapshot
Six angles, distilled from the data.
The stock is still in a corrective phase after a strong run, trading below both the 50-day and 200-day moving averages. It remains well off the 52-week high, but far above the 52-week low, which points to a mid-cycle reset rather than a broken long-term story.
Wall Street stays constructive: the consensus is Buy with a $110.09 target, above the current share price. Recent action has been mostly reaffirmations and target raises, with several firms lifting targets into the $102-$115 range and no fresh bearish calls.
The next report carries a mixed setup: BridgeBio has missed EPS in 6 of the last 7 quarters, but analysts still see a sharp improvement ahead. Consensus EPS for 2027 is near breakeven at $0.064763, so shareholders should watch whether revenue growth and margin leverage are finally translating into cleaner losses.
The pattern is net selling, led by CEO Neil Kumar, with 9 sales and no open-market buys. Most of the other activity is in-kind, exempt, or other non-discretionary filings, so the main signal is executive selling rather than broad insider accumulation.
The business still runs at a loss, but gross margin is strong at 94.4% and revenue growth is 120.4% year over year. Cash burn remains heavy, with operating cash flow of -$445.9 million and free cash flow of -$444.8 million, while debt of $2.73 billion exceeds cash of $587.5 million.
BridgeBio stands out for high-margin rare-disease assets and a pipeline that can support outsized revenue growth, but it is still earlier-stage than profitable peers. The valuation remains rich versus the sector, with the stock trading at a negative earnings multiple while the market prices in a much higher long-term target.
Similar companies
Peers in the same neighborhood.
- Market Cap
- $12.95B
- P/E
- -18.47
- Fwd P/E
- 1026.57
- PEG
- -1.43
- P/S
- 18.72
- P/B
- -5.15
- EV/EBITDA
- -24.50
- Div Yield
- 0.00%
- Gross Margin
- 93.14%
- Op Margin
- -78.56%
- Net Margin
- -100.64%
- ROE
- 31.67%
- ROIC
- -61.77%
Latest fiscal year · YoY change
- Revenue
- $502.08M+126.3%
- Gross Profit
- $473.81M+117.3%
- Op Income
- $-569,087,000
- Net Income
- $-729,306,000-36.1%
- EPS
- $-3.79-31.6%
- OCF Growth
- +14.4%
- FCF Growth
- +14.3%
- 52W High
- $93.42
- 52W Low
- $52.75
- 50D MA
- $76.32
- 200D MA
- $73.58
- Beta
- 0.97
- RSI (14)
- 35
- Avg Volume
- 2.74M
Earnings call summaries
Pick a quarter — each call distilled into takeaways, results, and a bull vs bear read.
BridgeBio posted another strong quarter for Attruby, with accelerating U.S. sales, supportive new kidney data, and all three late-stage programs now in regulatory review.· August 10, 2026
- Attruby net product revenue was $222.4 million, up from $71.5 million a year ago, and total revenue was $243.7 million versus $110.6 million last year.
- Attruby remained the fastest-growing brand in its space at 23% growth, while management said the overall ATTR-CM market grew 19% in the quarter and 51% year over year.
- New real-world and published kidney data strengthened the company’s differentiation story, including early sustained kidney protection signals and favorable hazard ratios versus placebo subgroups.
- All three late-stage programs moved into regulatory review: BBP-418 has a PDUFA date of November 27, 2026; encaleret has a PDUFA target date of May 8, 2027; and infigratinib NDA/MAA filings are underway.
- BridgeBio ended the quarter with $720.2 million in cash, then added $1 billion of preferred equity on July 1, bringing cash to about $1.7 billion.
- Management said the company expects continued Attruby growth, three potential launches over the next 12 months, and a path toward breakeven profitability in the relative near term.
Total revenues were $243.7 million for Q2 2026, up from $110.6 million in Q2 2025. Attruby net product revenue was $222.4 million versus $71.5 million a year ago; royalty revenue was $15.4 million versus $1.6 million; and license and services revenue was $5.8 million versus $37.4 million. Total operating expenses were $335.7 million versus $241.2 million last year, and the operating loss was $107.1 million compared with a $134.3 million loss in Q2 2025. As of June 30, 2026, cash, cash equivalents, and marketable securities were $720.2 million, and after the July 1 $1 billion preferred equity financing, cash was approximately $1.7 billion. Management did not provide formal revenue or EPS guidance on the call, but said Attruby remains on track for continued steady sales growth, and that BridgeBio believes its current cash position supports operating needs and three potential launches over the next 12 months.
Neil Kumar framed the quarter as a transition point for BridgeBio, saying the company is at “t equals zero” in its next chapter. He emphasized a stronger Attruby launch story built on clinical differentiation, real-world evidence, and newly published kidney-protection data, and said these could support broader use over the next 6 to 9 months. He also highlighted the broader pipeline, saying all three late-stage programs are now in regulatory review and that the company has a substantial set of future shots on goal.
Tom Trimarchi focused on the financial buildout behind the commercial expansion. He cited $243.7 million in revenue, $222.4 million in Attruby net product revenue, and a $107.1 million operating loss that improved about 20% year over year despite $335.7 million of operating expenses tied to launch preparation. He also noted $720.2 million in cash at quarter-end, followed by a $1 billion preferred equity investment led by Sixth Street, taking cash to about $1.7 billion and providing runway for three launches and continued Attruby investment.
Analysts focused heavily on how CARDIO-TTRansform affects Attruby’s position. Management said the failure of combination therapy supports stabilizers as the backbone of treatment, and Neil Kumar argued the data should enlarge the frontline pool while further reinforcing Attruby versus both knockdowns and tafamidis. Questions also centered on the kidney data, pricing, and market share assumptions; management said it does not plan to chase Pfizer on rebates, prefers clinical differentiation over price cuts, and will revisit market-share expectations after more complete CARDIO-TTRansform data and the ESC meeting. Additional questions covered launch readiness for BBP-418 and encaleret, ex-U.S. commercialization, and infigratinib’s achondroplasia market, with management emphasizing strong FDA interactions, payer interest, and confidence in global launches.
The call’s bullish case is that Attruby’s growth is still being driven by new patient starts, while the company now has a stronger scientific story from independent real-world evidence and kidney-protection data. Management repeatedly said the product is the only near-complete stabilizer, expects the frontline market to keep expanding, and believes the data should increasingly shift prescribing and guideline thinking in its favor. With three programs in regulatory review and $1.7 billion of cash, BridgeBio also looks funded to execute multiple launches.
The main risk is that the ATTR-CM market remains competitive and management acknowledged it is still early to know how much CARDIO-TTRansform will change prescribing or reimbursement. They also said first-line remains competitive and that gross-to-net could stay under pressure if Pfizer becomes aggressive, even though BridgeBio does not intend to cut price. More broadly, execution risk remains across three upcoming launches, and management said some of the expected commercial upside from the new kidney and RWE data may not show up for 6 to 9 months.
AI summary of the company's earnings call · Paraphrased · Not investment advice
- Free Float
- 86.4%
- Shares Outstanding
- 195.86M
- Float Shares
- 169.19M
of shares held by institutions
497 13F filers
Buy/sell ratio 0.36. Sells can include pre-scheduled 10b5-1 plan sales, not just discretionary selling.
Congressional trading
Senate and House stock disclosures for BBIO, newest first.
| Member | Type | Traded | |
|---|---|---|---|
| Gilbert Ray CisnerosHouse · CA31 | Buy | May 11, 26 | Filing → |
| Gilbert Ray CisnerosHouse · CA31 | Buy | Apr 29, 26 | Filing → |
| Gilbert Ray CisnerosHouse · CA31 | Buy | Mar 3, 26 | Filing → |
| Gilbert Ray CisnerosHouse · CA31 | Buy | Mar 19, 26 | Filing → |
| Gilbert Ray CisnerosHouse · CA31 | Buy | Mar 18, 26 | Filing → |
| Gilbert Ray CisnerosHouse · CA31 | Buy | Sep 22, 25 | Filing → |
| Gilbert Ray CisnerosHouse · CA31 | Buy | Aug 8, 25 | Filing → |
Source: public STOCK Act disclosures. Filed weeks after the trade — a lagging signal, not a real-time one.
Top institutional holders
Largest 13F positions, with quarter-over-quarter change.
| Holder | Shares | Δ Quarter |
|---|---|---|
| Vanguard Group Inc | 16.86M | ▲ 30.63K |
| Jupiter Topco LLC | 14.11M | ▲ 14.11M |
| Kohlberg Kravis Roberts & Co. L.P. | 13.26M | 0 |
| Janus Henderson Group Ltd. | 13.18M | ▲ 2.18M |
| Farallon Capital Management LLC | 10.74M | ▲ 1.38M |
| Blackrock, Inc. | 10.29M | ▼ 3.92M |
| Viking Global Investors LP | 9.95M | ▼ 1.89M |
| Vanguard Capital Management LLC | 7.90M | ▲ 139.48K |
| Vanguard Portfolio Management LLC | 7.66M | ▼ 423.85K |
| Wellington Management Group Llp | 5.31M | ▲ 2.82M |
| Two Sigma Investments, LP | 4.72M | ▲ 1.60M |
| Aisling Capital Management LP | 4.59M | ▼ 500.00K |
Held by 449 ETFs
Biggest fund positions in BBIO by dollar value.
Recent insider transactions
Who's buying, who's selling, and how much.
| Date | Insider | Type | Shares |
|---|---|---|---|
| Sep 17, 26 | Kumar Neil | sell | 8,721 |
| Sep 17, 26 | Kumar Neil | sell | 1,279 |
| Aug 19, 26 | Kumar Neil | sell | 8,100 |
| Aug 19, 26 | Kumar Neil | sell | 1,800 |
| Aug 19, 26 | Kumar Neil | sell | 100 |
| Aug 18, 26 | Kumar Neil | sell | 1,900 |
| Aug 18, 26 | Kumar Neil | sell | 17,279 |
| Aug 18, 26 | Kumar Neil | sell | 14,602 |
| Aug 18, 26 | Kumar Neil | sell | 1,199 |
| Aug 16, 26 | Trimarchi Thomas | other | 22,781 |
A “Sell” may be a pre-scheduled 10b5-1 plan sale rather than a discretionary decision — read insider selling with that in mind.
Our BBIO coverage
Recent articles, reports, and earnings notes.

BridgeBio Pharma (BBIO): Attruby Drives a Rare-Disease Breakout
BridgeBio has evolved from a pipeline biotech into a commercial-stage rare-disease story, led by explosive Attruby sales and a late-stage pipeline. The stock still carries meaningful balance-sheet risk, but the launch momentum is real.

ADARx Pharmaceuticals IPO Preview: RNA Pipeline Meets Cash Burn
ADARx Pharmaceuticals is expected to list on NASDAQ on 2026-09-25, with shares priced in a $15.00 to $17.00 range. The company is offering 21,875,000 shares and has disclosed an implied market cap of $427,656,250. The setup favors investors who want late-stage RNA exposure, but the key watch item is whether the market gives credit to the pipeline before more clinical data arrives.

BridgeBio Pharma, Inc. (BBIO) climbs 11% on ATTR-CM news
BridgeBio Pharma, Inc. (BBIO) climbs after hours as a rival ATTR-CM therapy suffers a late-stage setback, improving the outlook for Attruby. The move comes on top of strong sales momentum, fresh financing flexibility, and bullish analyst support, giving the rally more substance than a typical trading pop.
Want a deeper read on BBIO?
Generate a full analyst-grade report — bull/bear case, price targets, valuation depth, and a complete financial breakdown.
BridgeBio Announces FDA Acceptance and Priority Review of NDA for Oral Infigratinib for Children with Achondroplasia
globenewswire.com · Oct 6
BridgeBio and Community Partners Launch Nationwide ATTR-CM Education Effort Ahead of World Amyloidosis Day
globenewswire.com · Oct 5
BBP-418 Demonstrates Potential to Be Disease Modifying Therapy, Restoring Cardiac and Disease Markers to Unaffected Levels
globenewswire.com · Oct 5
BridgeBio Pharma Eyes Four Global Launches by 2027 as Attruby Nears Blockbuster Status
marketbeat.com · Sep 26
BridgeBio Pharma Eyes Four Global Launches by 2027 as Attruby Nears Blockbuster Status
defenseworld.net · Sep 26
BridgeBio Pharma, Inc. (BBIO) Presents at Bernstein Insights: Healthcare Leaders and Disruptors - 3rd Annual Healthcare Forum Transcript
seekingalpha.com · Sep 23
Acoramidis Demonstrates Real-World Benefit Versus Tafamidis in ATTR-CM, Reducing Risk of Clinical Worsening
globenewswire.com · Sep 23
BridgeBio Pharma Reports Inducement Grants under Nasdaq Listing Rule 5635(c)(4)
globenewswire.com · Sep 18
Headlines from third-party outlets — TickerSpark isn't affiliated with these sources.
AI analysis · Last refreshed September 30, 2026 · Live quote · Not investment advice